#266

Jellyfish Age Backwards

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Molecular biologist Nicklas Brendborg chats with Trey Elling about JELLYFISH AGE BACKWARDS: NATURE’S SECRETS TO LONGEVITY. Topics include:

  • Why we age (:51)
  • How a certain jellyfish ages backwards (1:29)
  • The unique aging of salmon (2:26)
  • Large animals outliving small ones (3:17)
  • The curious case of the naked mole rat (4:19)
  • Genetics and lifespan (6:49)
  • Why eradicating major diseases wouldn’t extend average lifespan (9:20)
  • Distinguishing the queen bee from worker bees (12:04)
  • Antioxidant supplements bad for our health? (12:59)
  • Hormesis (14:30)
  • Heat shock proteins (16:25)
  • Human growth hormone (19:30)
  • Insulin-like Growth Factor 1, aka IGF-1 (21:25)
  • Rapamycin and fungi (2:22)
  • Spermadine (25:43)
  • Telomeres (26:44)
  • The epigenetic clock (28:33)
  • Do old people benefit from young blood transfusions (34:13)
  • The microbiome and aging (36:31)
  • Fecal transplants (39:06)
  • Caloric restriction (40:05)
  • Insulin and the aging process (45:45)
  • Metformin (48:33)
  • Exercise (51:35)